Metabolic Health

Examine the Interplay between Cardiovascular and Metabolic Health

with Digital Vascular Biomarkers

Fast Facts

98M

adults in the US have prediabetes, more than 8 in 10 don’t know they have it.1

38M

adults in the US have diabetes, 1 in 5 don’t know they have it.2

2X

Medical costs for people with diabetes are more than twice as high as for people who don’t have diabetes.3

The Connection Between Arterial Stiffening and Metabolic Health

  • Hwang HS, Ko KP, Kim MG, et al.

    Subjects with abnormal metabolic conditions have increased arterial stiffness independent of age and BP which may contribute to the development of cardiovascular disease.

    Hwang HS, Ko KP, Kim MG, et al.
    Clinical Hypertension
  • Firmino, Wende, Gregorio, et al.

    Patients with prediabetes present early markers of cardiac dysfunction and arterial stiffness.

    Firmino, Wende, Gregorio, et al.
    Annals of Vascular Surgery
  • Monika Starzak, Agata Stanek, Grzegorz K. Jakubiak et. al.

    Increased arterial stiffness (AS) can predict the development of cardiovascular disease both in the general population and in patients with Metabolic Syndrome (MS).

    Monika Starzak, Agata Stanek, Grzegorz K. Jakubiak et. al.
    Int J Environ Res Public Health

Arterial Stiffness and Metabolic Health

Metabolic health and arterial stiffness are closely linked, significantly affecting cardiovascular wellness. Conditions like insulin resistance, abnormal lipid levels, and obesity can accelerate arterial stiffness, increasing the risk of hypertension and heart disease. Optimal metabolic health, achieved through lifestyle modifications and medical management, is essential for reducing arterial stiffness and improving heart health.

Research Highlights

Diabetes and Cardiovascular Risk

Vascular biomarkers play a crucial role in managing diabetes by facilitating the early detection of cardiovascular risks linked to metabolic disorders, evaluating the effectiveness of treatments, and personalizing medical approaches. These biomarkers help in understanding the impact of metabolic factors on vascular aging and can predict future cardiovascular events, enabling proactive and targeted interventions to improve overall health outcomes.

Utility of Vascular Biomarkers in Metabolic Health

  • Prince CT, Secrest AM, Mackey RH, Arena VC, et al.

    PWA measures, particularly AP and SEVR, are associated with both renal damage and poor renal function in type 1 diabetes.

    Prince CT, Secrest AM, Mackey RH, Arena VC, et al.
    Diabetes & Vascular Disease Research
  • Marcon D, Tagetti A, Piona C, Giontella A, et al.

    The independent association between cBP and markers of subclinical vascular damage underlines the importance of haemodynamic factors in the development of early signs of macrovascular disease in T1D patients.

    Marcon D, Tagetti A, Piona C, Giontella A, et al.
    Journal of Hypertension
  • Tougaard NH, Theilade S, Winther SA, Tofte N, et al.

    [In people with type 1 diabetes mellitus,] higher carotid-femoral pulse wave velocity (cfPWV) was associated with increased hazard of progression in albuminuria, decline in eGFR ≥30%, cardiovascular event, mortality, and the composite renal end point.

    Tougaard NH, Theilade S, Winther SA, Tofte N, et al.
    Journa of American Heart Association

Incorporate Vascular Biomarkers in the Management of Diabetes

Download Reimbursement Guide

In-Clinic

  • Enhance cardiovascular risk stratification and personalize management plans for diabetic patients.
  • Tailor and adjust treatment strategies, improving both metabolic and vascular health outcomes.
  • Reimbursable with CPT 93050.

At Home

  • Empower patients to actively manage their health by tracking changes in their biomarkers.
  • Integration with telemedicine to maintains an ongoing patient-provider interaction and enhances personalized care.
  • Reimbursable with CPT 9945x & 99091.

1, 2, 3 CDC Diabetes Fast Facts