Chronic Obstructive Pulmonary Disease (COPD)

Navigate the Cardiovascular Implications of COPD

with Digital Vascular Biomarkers

Fast Fact

16M

In the United States, COPD affects nearly 16 million adults, and many more do not know they have it.1

The Connection Between Arterial Stiffening and COPD

Arterial Stiffness and COPD

Arterial stiffness in COPD patients worsens cardiovascular issues and decreases oxygen delivery, thereby increasing the disease's complications. This condition, fueled by chronic inflammation, increases the heart's workload and risks of heart failure, leading to more frequent exacerbations and higher mortality. Effective management of arterial stiffness is essential for improving COPD treatment outcomes.

Research Highlights

Power of Vascular Biomarkers

Vascular biomarkers offer essential insights into the cardiovascular aspects of COPD, particularly arterial stiffness, which is commonly elevated due to systemic inflammation and endothelial dysfunction. These biomarkers enable clinicians to precisely evaluate arterial stiffness, facilitating focused cardiovascular management for COPD patients.

Utility of Vascular Biomarkers in COPD

  • Sabit R, Bolton CE, Edwards PH, Pettit RJ, et al.

    The increase in aortic pulse wave velocity (PWV) in patients and the associated changes in pulse pressure and augmentation index (AIx) validate our hypothesis that increased arterial stiffness is a systemic complication of COPD.

    Sabit R, Bolton CE, Edwards PH, Pettit RJ, et al.
    American Journal of Respiratory and Critical Care Medicine
  • Aksenova TA, Gorbunov VV, Tsarenok SY.

    In patients with a combination of hypertension and COPD the increase in PWV, systolic and pulse pressure in the ascending aorta was observed, compared to patients with isolated hypertension or isolated COPD.

    Aksenova TA, Gorbunov VV, Tsarenok SY.
    Russian Therapeutic Archive
  • Bolton CE, Stocks J, Hennessy E, et al.

    Increased pulse wave reflection, manifested as an increased AIx value, is independently associated with impaired lung function in children born at 25 weeks of gestation or less compared with term-born classmates at age 11 years. Importantly, these abnormal large vessel hemodynamics are not reflected in peripheral BP...

    Bolton CE, Stocks J, Hennessy E, et al.
    The Journal of Pediatrics

Incorporate Vascular Biomarkers in the Management of COPD

Download Reimbursement Guide

In-Clinic

  • Enhance cardiovascular risk stratification and personalize management plans for COPD patients.
  • Tailor and adjust treatment strategies to improve health outcomes.
  • Reimbursable with CPT 93050.

At Home

  • Empower patients to actively manage their health by tracking changes in their biomarkers.
  • Integration with telemedicine enables ongoing patient-provider interaction and enhances personalized care.
  • Reimbursable with CPT 9945x & 99091.

1 Source - What is COPD